The result suggested that mangiferin present in mango extracts may have health promoting effects in diseases related to the impaired formation of new blood vessels.
The formation of new blood vessels is an important therapeutic target for diseases such as limb ischemia, coronary infarction or stroke.
Mangiferin is a natural C-glucoside xanthone.
The easiest source of mangiferin, is the mango plant – Mangifera indica, especially the leaves of the plant. Stem bark, heartwood and roots of Mangifera indica also yield mangiferin.
Mangiferin protected against gastric injury by ethanol and indomethacin most possibly through the antisecretory and antioxidant mechanisms.
Mangiferin also together with epigallocatechin gallate has been found to be able to have protective effect on lipid peroxidation in red blood cells, possibly due to its antioxidant activity.
Mangiferin in mango